@flypapers@biologists.social

· 5mo ago

📰 "Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila"
https://www.biorxiv.org/content/10.64898/2026.04.23.720414v1?rss=1
#Metabolism #Circadian
#Drosophila #Behaviour

bioRxiv

Bidirectional regulation between circadian feeding behavior and specialized midgut clocks in Drosophila

Feeding is a fundamental animal behavior. Increasing evidence suggests that the timing of food intake—rather than the amount or quality alone—contributes to maintaining health. Although mistimed eating can reset peripheral clocks and desynchronize them from central pacemakers to affect physiology and metabolism, how peripheral clocks can in turn shape rhythmic feeding behavior is less well understood. Here, we investigated the contribution of peripheral clocks to circadian feeding behavior in Dr

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flypapers @flypapers@biologists.social

· 5mo ago

📰 "Glucose is dynamically regulated by time of day in humans and Drosophila"
https://doi.org/doi:10.1371/journal.pbio.3003717
https://pubmed.ncbi.nlm.nih.gov/41989995/
#Circadian
#Metabolism #Drosophila

doi.org

Glucose is dynamically regulated by time of day in humans and Drosophila

Circadian clocks are known to regulate metabolism, but the details of how they regulate glucose processing remains unclear. By integrating human metabolite profiling with isotope-tracing in Drosophila, this study defines daily rhythms in glucose utilization that are influenced by circadian timing.

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flypapers @flypapers@biologists.social

· 5mo ago

📰 "Circadian clock gates diurnal glucose utilization"
https://doi.org/doi:10.1371/journal.pbio.3003743
https://pubmed.ncbi.nlm.nih.gov/41996297/
#Circadian
#Metabolism #Drosophila #Sleep

doi.org

Circadian clock gates diurnal glucose utilization

The circadian clock and cellular metabolism are tightly coupled. This primer discusses a recent PLOS study that elucidates how glucose metabolism changes over the course of the day in Drosophila and how this is disrupted in clock and sleep mutants.

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